Common anticholinergic drugs like Benadryl linked to increased dementia risk
A report published in JAMA Internal Medicine several years ago highlighted a link between long-term use of anticholinergic medications like Benadryl and dementia. While this study and other observational studies have also found this association, it doesn’t prove that these drugs cause dementia. But we do know that anticholinergic drugs can cause confusion and increase fall risk in older people.